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Frank Alber

FrankĀ Alber
Program
Beckman Young Investigators

Award Year
2012

Institution
University of Southern California

Email:
alber@usc.edu

Website:
http://www.cmb.usc.edu/people/alber/Personal_Alber.html

Research Title:
Tissue-specific 3D genome organizations: structural determination, functional implication and folding principles

Abstract:
The broad theme of my research is to expand the scope of structural biology from studying molecular functions of isolated macromolecules to characterizing their cellular organization and their cooperative roles in cellular processes. My current focus is in determining structures of large macromolecular assemblies at resolutions ranging from atomic to nano-scale, and detecting their abundance, orientations and locations within the crowded cellular environment. Specifically, we are interested in the spatial organization of the nucleoplasm and the genome.

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