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Zachary Pincus

Zachary Pincus
Program
Beckman Young Investigators

Award Year
2016

Institution
Washington University St. Louis

Email:
zpincus@wustl.edu

Website:
http://zplab.wustl.edu

Research Title:
The origins of Individuality: Developmental determinants of health & lifespan

Abstract:
Why do some individuals live longer, age more gracefully, or have greater reproductive success than others? Though differing genetic background and environmental conditions  play a role, even genetically identical organisms reared in homogeneous environments differ markedly in lifespan, fecundity, and tolerance to stressors. I hypothesize that variability in adult health and disease among otherwise identical individuals originates from stochastic fluctuations in organismal development. I will present my lab's initial progress in understanding how organisms address such “biological noise” in development and aging.

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