Research Summary
The Marshall Lab investigates the underlying pathological mechanisms of Alzheimer’s disease. Our research focuses on the microtubule-associated protein tau and glutamatergic NMDA receptors. We are specifically interested in elucidating how the synaptic location of NMDA receptors influences the development and progressive spread of aggregated tau in Alzheimer’s disease cell models. Our work continues to explore novel pathological characteristics distinct to Alzheimer’s compared to other neurodegenerative diseases, as well as potential disease-modifying effects of NMDA receptor pharmacological compounds.
“I discovered the transformative nature of undergraduate research while I was a college student. During this period of self-discovery, the Beckman Scholar’s Program provides undergraduate students the opportunity to envision, initiate, and fortify their scientific careers. I am honored to serve as a member of the BSP Executive Committee and look forward to supporting the Foundation’s vision of inclusive excellence in undergraduate research.