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Arnold O. Beckman Postdoctoral Fellow Anna Simon, PhD, publishes: Exploiting the conformational-selection mechanism to control the kinetics of a "smart" DNA hydrogel

Learn more about what 2017 AOB Postdoc Anna Simon (University of Texas Austin) has been working on:


The sequence-specific hybridization and molecular recognition properties of DNA support the construction of stimulus-responsive hydrogels with precisely controlled crosslink geometry. Here we show that, as predicted by the conformational selection mechanism, the response kinetics of such a hydrogel can be tuned over orders of magnitude by modulating the thermodynamic stability of its crosslinks.


Anna Julia Simon, Luke T. Walls-Smith and Kevin W. Plaxco


DOI: 10.1039/C8AN00337H

Anna Simon W-1790