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Stavroula Hatzios W-1853

Dr. Stavroula Hatzios, PhD

  • Award Recipient

Research Summary

The rapid diagnosis and treatment of bacterial infections is critical for controlling the spread of disease. However, selectively targeting disease-causing bacteria in complex microbial communities, like those found in the human gut, remains a significant challenge. Our proposal will draw on fundamental principles of protease biochemistry, chemical biology, and infection models to develop new probes and antimicrobials for the precise detection and inhibition of pathogenic microbes in the gut. Such technologies could help target difficult-to-treat pathogens, minimize collateral damage to beneficial gut microbes, and form the basis of new point-of-care diagnostics to improve infection outcomes in resource-limited settings.

Research Title:

Precision Tools for the Selective Detection and Inhibition of Bacterial Pathogens in Complex Microbial Communities

Award Year: 2020
Institution at Time of Award: Yale University